Loss of viability after disulfiram treatment without preceding depletion of intracellular GSH.
نویسندگان
چکیده
منابع مشابه
Disulfiram Treatment of Alcoholism
P to the completion of this welldesigned scientific study, which was conducted at nine Veterans Administration Medical Centers, the medication disulfiram (Antabuse®) was controversial in the treatment of alcoholism. The controversy over its efficacy was rooted in the lack of sophisticated scientific data on which to base its effectiveness. Fuller and colleagues used stateoftheart clinical r...
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چکیده ندارد.
15 صفحه اولIntracellular GSH Depletion Triggered Mitochondrial Bax Translocation to Accomplish Resveratrol Induced apoptosis in U937 cell Line
Affiliations: Department of Biochemistry, Dr. B.C. Roy Post Graduate Institute of Basic medical Sciences & I.P.G.M.E.&R, 244B, Acharya Jagadish Chandra Bose Road, Kolkata700020, India (P. G., A. D. and S. K. B.), Department of Pharmacology, Dr. B.C. Roy Post Graduate Institute of Basic medical Sciences & I.P.G.M.E.&R, Kolkata-700 020 (R. S. and M. C.), Bio-Organic Division, Bhabha Atomic Resear...
متن کاملSpectroscopic Characterization of Disulfiram and Nicotinic Acid after Biofield Treatment
Disulfiram [bis(diethylthiocarbamoyl)disulphide] is an antabuse drug, being used clinically as an aid to the treatment of chronic alcoholism. It is the first drug approved by US Food and Drug Administration to treat the alcohol addiction [1]. Alcohol (ethanol) transforms into acetaldehyde by alcohol dehydrogenase enzyme, which further oxidized to acetic acid by acetaldehyde dehydrogenase (ADH) ...
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ژورنال
عنوان ژورنال: The Journal of Toxicological Sciences
سال: 1990
ISSN: 0388-1350,1880-3989
DOI: 10.2131/jts.15.63